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Why Does Soy Reduce Estrogen Levels In Studies?

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Old 12-13-2017, 01:36 PM
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Default Why Does Soy Reduce Estrogen Levels In Studies?

Soy is widely known in health circles as pro-estrogenic and feminizing and men are recommended to avoid it. If that’s actually the case, can anyone explain why serum estrogen levels actually decrease in soy-supplemented groups in studies in both men and women? And why is there an inverse relationship between hormone dependent cancers such as breast and prostate cancer (I suppose all cancers are hormone dependent) and soy consumption? Here are just some of the studies I’m talking about:

ncbi.nlm.nih.gov/pubmed/8770469 - 36-oz of daily soymilk consumption for a month significantly decreased serum 17 beta-estradiol levels in premenopausal women.

ncbi.nlm.nih.gov/pubmed/9839524 - Estrone and estradiol levels were decreased by 23% and 27% at the end of the study in the soy milk supplemented group in Japanese women. The change in estrone and estradiol levels was minor in the control, non-soy group.

ncbi.nlm.nih.gov/pubmed/11303585 - Serum estrone concentrations decreased in the soy-supplemented group in Japanese men. There was no change in testosterone levels in both the soy group and the control group.

Is it that the estrogen circulation in blood decreases from soy but estrogen level inside the cell increases? Is that why soy is so widely considered as ‘estrogenic’?
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Old 12-13-2017, 02:26 PM
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I haven't looked at those studies. But often, there is the PDF available to download. It will give the details of the study in question.
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Old 02-21-2018, 06:10 PM
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Soybeans are source of proteins and dietary staple in some cultures. Soy contains phytoestrogens known as isoflavones that mimic the activity of estrogen hormone in the body. The effects of soy isoflavones on human estrogen levels is complex. Soy can be consumed by everybody and has a modest effect on estrogen levels.
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