It all depends on how much you currently weigh and how much your daily caloric need is. Once you find that out (fitday is a great tool) people generally say to restrict 500 calories a day, and that should take you to lose 1 lb per week.
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Yo-yo dieter, female, height: 5' 4.5"
07/19/10: 187 lb
12/16/10: 165.2 lb
04/29/12: 202.5 lb 
Current: 202.5 lb
Goal #1: 185 lb by 06/10/2012
Goal #2: 170 lb by 08/10/2012
Goal #3: 155 lb 10/13/2012
Final goal: 135 lb  12/20/2012
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