I second what frenchhen said - the most important thing for me has been to not set myself up for failure by setting goals that have strict time limits or too-high amounts. That being said, it's important to have some kind of mini goals in mind, just to keep yourself going. I don't know that it's really that important if you do 10 mini goals or 18 mini goals. However, I do find it motivating when I see a new second digit on the scale - you know, 190 to 180. Something about that flip in number makes it seem all the more real. So, I guess if I had to pick one, I'd say 18 goals of 10 lbs.
Starting weight: 192.0 lbs (6/19/2011)
Lowest weight: 154.6 (6/25/2012)
Current weight: 162.8 lbs (1/28/2013)
Total lost: 29.2 lbs
Goal: 132 lbs