I went into menopause in my 40's. I gained weight in my early 40's from an SSRI antidepressant and have been struggling ever since. The whole calories in and calories out no longer applies. I'm now 55 yrs old and have been working with a weight loss coach as well as a Naturopathic doctor. Neither has been able to figure out what the problem is. I've done HCG through 3 protocols, each time losing about 17 -25 lbs in 40 days. This last round I've gained back 8 lbs already in a month eating between 1200 and 1400 cals a day (high protein, high fat, low carb). Every single morning the scale comes up higher by a small amount. Not sure why I'm sharing except to let others know that they aren't alone. The rules that applied in my 30's and early 40's no longer apply. Simple diet and exercise alone haven't worked for me yet. I am not even a binge eater so I can't blame it on that. My weight is 30 lbs higher than it was in my 30's and I'm eating almost half as many calories as I did then.