I think it's important to pay attention to the timing of supplements and also the combination of macronutrients during a meal.
I take both magnesium and calcium supplements every day. Mg because there's evidence that the RDA should be set higher, to 500 mg, plus it's a very important mineral and difficult to get even when eating clean. Calcium because I limit my dairy products. But taking Mg and Ca at the same time is bad, as Mg negatively affects the absorption of Ca.
So timing really is very important and I don't think it can be stressed enough.
Think of food as fuel for the body instead of feeding emotions